Cytoxan cardiomyopathy
WebOct 11, 2024 · Weakening of the heart muscle (cardiomyopathy) Heart rhythm problems (arrhythmia) Heart attack Stroke High blood pressure Blood clots Whether you're at risk for heart problems during and after cancer treatment depends on how healthy your heart is and the specific drugs you'll be receiving. WebNov 1, 1999 · It seems unlikely that the cyclophosphamide treatment caused the cardiomyopathy as the dose was low (1.5 mg/kg/day, total dose <200 mg/kg). This is at the lowest end of the dose range for cardiac toxicity. There was no suggestion of a dosing error causing an iatrogenic problem.
Cytoxan cardiomyopathy
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WebAug 11, 2024 · It is a chemotherapy drug that works by slowing or stopping cell growth. Cyclophosphamide also works by decreasing your immune system 's response to various diseases. It is used to treat a certain type of kidney disease in children after other treatments have not worked. WebCardiovascular adverse events in patients with non-Hodgkin lymphoma treated with first-line cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) or CHOP with rituximab (R-CHOP): a systematic review and meta-analysis None. None.
WebJan 1, 2013 · Cyclophosphamide is increasingly used to treat various types of cancers and autoimmune conditions. Higher doses of this drug … WebJan 1, 2013 · Cyclophosphamide is increasingly used to treat various types of cancers and autoimmune conditions. Higher doses of this drug may produce significant cardiac toxicity, including fatal hemorrhagic myocarditis. In this review, we present a case of cyclophosphamide-induced cardiomyopathy requiring mecha …
WebFatal cardiomyopathy developed in two patients receiving cyclophosphamide in preparation for bone marrow transplantation. Both patients had normal EKGs prior to receiving cyclophosphamide in total doses of 168 mg/kg (case 1) and 144 mg/kg (case 2) and subsequently developed loss of voltage and ST-T wave changes. WebNov 15, 2024 · Manifestations of cardiomyopathy range from microscopic alterations in cardiac myocytes to fulminant heart failure with inadequate tissue perfusion, fluid accumulation, and cardiac rhythm ...
WebMay 1, 2016 · The incidence of congestive cardiomyopathy is approximately 7% as long as the cumulative doxorubicin dose is <550 mg/m 2 [4]. However, in elderly patients with B-cell lymphoma treated with CHOP ± rituximab, congestive cardiomyopathy was reported in one third to one half of the patients [1], [5].
WebJun 22, 2024 · Doxorubicin (trade name Adriamycin) is a commonly used chemotherapy agent that is very effective in both Hodgkin and Non-Hodgkin lymphomas. 1 It is used in virtually all the first-line chemotherapy regimens for lymphomas. It belongs to the class of chemotherapy drugs called anthracyclines. Hero Images / Getty Images small round office table and chairsWebCyclophosphamide and Cardiomyopathy - a phase IV clinical study of FDA data Summary: Cardiomyopathy is found among people who take Cyclophosphamide, especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months. The phase IV clinical study analyzes which people take Cyclophosphamide and have … small round occasional tableWebJul 14, 2014 · Cyclophosphamide-induced cardiotoxicity (CIC) is a well-known adverse effect and not that uncommon [ 1 ]. Symptoms occur usually within 1 to 3 weeks, and although in some patients cardiotoxicity resolves without late consequences, the mortality rate can be as high as 43% [ 2 – 4 ]. Drug side effects are usually seen after a single … small round office table with chairsWebCyclophosphamide-induced cardiomyopathy: a report of two cases and review of the English literature. Fatal cardiomyopathy developed in two patients receiving cyclophosphamide in preparation for bone marrow transplantation. Both patients had normal EKGs prior to receiving cyclophosphamide in total doses of 168 mg/kg (case 1) … highmark health corporate structureWebMay 1, 1981 · • The cardiac effects of chemotherapeutic regimens using high doses of cyclophosphamide (180 mg/kg over four days) were assessed in 32 patients with hematologic malignant neoplasms. Left ventricular systolic function, determined by the fractional shortening on echocardiogram, declined substantially five to 16 days after the … highmark health employee advantageWebApr 2, 2024 · Cardiomyopathy (kahr-dee-o-my-OP-uh-thee) is a disease of the heart muscle that makes it harder for the heart to pump blood to the rest of the body. Cardiomyopathy can lead to heart failure. The main types … small round ottoman coverWebAbstract. A 17-year-old man with mediastinal seminoma was treated with chemotherapy and mediastinal irradiation therapy. Then he received high-dose chemotherapy containing cyclophosphamide (CY) followed by autologous peripheral blood stem cell transplantation. He suffered from CY-induced cardiomyopathy beginning six days after the ... small round orange pill 5