WebApr 23, 2024 · CTCF binding sites are mutation hotspots in cancer, while mutations in CTCF itself lead to intellectual disabilities, emphasizing its importance in disease etiology. In this review we cover various aspects of CTCF function, revealing the polyvalence of this factor as a highly diversified tool for vertebrate genome organization and transcription ... WebPreviously, it was shown that the CTCF paralogous gene, BORIS (brother of the regulator of imprinted sites) is expressed in male germ cells, but its function in spermatogenesis has not been defined. ... By gene expression profiling, we found that transcript levels for Gal3st1 (also known as cerebroside sulfotransferase [CST]), known to play a ...
CTCF Antibody Cell Signaling Technology
Webchip antibody: CTCF (CST, Cat# 2899) Treatment protocol: For inducing auxin-inducible degron system, 500μM 3-indole acetic acid was treated for 6 hours. Growth protocol: CTCF degron cells were cultured in RPMI1640 medium supplemented with 10% FBS, 100U/ml Penicillin and 100μg/ml Streptomycin. Extracted molecule: genomic DNA: Extraction … WebMar 11, 2014 · CCCTC-binding factor (CTCF) is a DNA-binding protein that has various, often seemingly contradictory, roles in gene regulation. This Review describes these disparate functions and how the context ... north hills private school
CTCF: a Swiss-army knife for genome organization and ... - PubMed
WebMonoclonal Antibody for studying CTCF. Cited in 110 publications. Validated for WB, IP, IHC, IF, IF, ChIP, ChIP, C&R. Available in 2 sizes. Highly specific and rigorously validated in-house, CTCF (D31H2) XP® … WebJun 22, 2024 · Although CTCF is a well-established 3D chromatin organizer in multicellular eukaryotes, relatively little is known about its male germ cell-specific paralogue, BORIS. … WebJun 5, 2015 · CCCTC-binding factor (CTCF) is an 82-kDa protein with 11 zinc fingers. 1 It was first identified as a transcriptional repressor of the chicken c-myc gene, a regulatory … north hills public library