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WebDec 2, 2024 · AbstractPurpose:. HER3 is a compelling target for cancer treatment; however, no HER3-targeted therapy is currently clinically available. Here, we produced U3-1402, an anti-HER3 antibody–drug conjugate with a topoisomerase I inhibitor exatecan derivative (DXd), and systematically investigated its targeted drug delivery potential and antitumor … WebSynonyms for CLODS: lumps, hulks, morons, idiots, losers, brutes, oafs, louts; Antonyms of CLODS: brains, thinkers, intellectuals, sages, geniuses, genii, wizards ... hall palladian house in norfolk
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